Endocrine Abstracts

A 76yr old lady presented to A&E with 'collapse and fall', 2 days following self-discharge for the same complaint. She had a medical history of type 2 diabetes on Gliclazide 80 mg o.d. and osteoarthritis of the spine.She was noted to be tanned with pigmented palmar creases and had marked postural hypotension. Biochemistry showed serum sodium 124 millimols per litre, potassium 4.6 millimols per litre and cortisol 43 nanmols per litre. A short synacthe...

Case A:A 15 year old girl was found to have a sellar mass on MR in the course of investigations for secondary amenorrhoea. Prolactin was normal at 305 milliunits per litre and random coritsol was 92 nanomols per litre. She was lost to follow up, but re-presented 2 years later with lethargy and headaches. Investigations revealed hypopituitarism with low free T4, gonadotrophins, prolactin, oestradiol, and peak cortisol of 85 nanomols per litre and undetectable GH with insuli...